Scaling Agentic Inference Across Heterogeneous Compute [Zain Asgar] – 757

In this episode, Zain Asgar, co-founder and CEO of Gimlet Labs, joins us to discuss the heterogeneous AI inference across diverse hardware. Zain argues that the current industry standard of running all AI workloads on high-end GPUs is unsustainable for agents, which consume significantly more tokens than traditional LLM applications. We explore Gimlet’s approach to heterogeneous inference, which involves disaggregating workloads across a mix of hardware—from H100s to older GPUs and CPUs—to optimize unit economics without sacrificing performance. We dive into their "three-layer cake" architecture: workload disaggregation, a compilation layer that maps models to specific hardware targets, and a novel system that uses LLMs to autonomously rewrite and optimize compute kernels. Finally, we discuss the complexities of networking in heterogeneous environments, the trade-offs between numerical precision and application accuracy, and the future of hardware-aware scheduling.

🗒️ For the full list of resources for this episode, visit the show notes page: https://twimlai.com/go/757.

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🔗 LINKS & RESOURCES
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Gimlet Labs Emerges from Stealth with 8-Figure Revenues, Fundamentally Shifting the Paradigm in How Agentic AI Workloads Are Run and Opening Up New Compute Capacity – https://www.globenewswire.com/news-release/2025/10/22/3171079/0/en/Gimlet-Labs-Emerges-from-Stealth-with-8-Figure-Revenues-Fundamentally-Shifting-the-Paradigm-in-How-Agentic-AI-Workloads-Are-Run-and-Opening-Up-New-Compute-Capacity.html
Gimlet Labs – https://gimletlabs.ai/
Benchmarking AI-generated CUDA kernels on an H100 – https://gimletlabs.ai/blog/ai-generated-cuda-kernels
Speeding up PyTorch inference on Apple devices with AI-generated Metal kernels – https://gimletlabs.ai/blog/ai-generated-metal-kernels
Qualcomm’s AI250 Attacks the AI Inference Memory Bottleneck | Durga Malladi Interview – https://youtu.be/acuSJeDRpIc
Closing the Loop Between AI Training and Inference with Lin Qiao – 742 – https://twimlai.com/podcast/twimlai/closing-the-loop-between-ai-training-and-inference/

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